LifeChoices' pregnancy tests are highly
sensitive urine-based tests that can be confidentially used
to indicate pregnancy. They are laboratory-quality, with a
99.9% accuracy rate. This page is designed to provide
information about using and reading the tests.
What is hCG?
Human chorionic gonadotropin, or hCG, is a protein
hormone produced by the placenta.
What does hCG have to do with pregnancy tests?
Urine-based pregnancy tests analyze the presence of hCG.
The appearance and increased levels of hCG provide an
excellent indicator of pregnancy. hCG is released into
the mother's circulation almost immediately after
implantation (5 - 8 days after conception). hCG is
produced in minute amounts and then, rising
exponentially, the concentration doubles approximately
every 2.2 days.
Do all pregnancy tests have the same sensitivity to
hCG?
No. There are many types of tests on the market for both
professional and home use. They have different
sensitivity levels for detecting hCG. Some
over-the-counter home tests only detect 150-250mIU's of
hCG. This means they may not pick up the pregnancy until
well after the first missed period. Our test, one of the most sensitive urine-based
tests available, detects concentrations as low as 20 mLU/ml
Are the levels of hCG in all pregnant women the same
in any given week of pregnancy?
No. The production of hCG can vary greatly from women to
women in any given week of pregnancy with as much as a
20-fold variation in individual levels. Some women with
high hCG may come up positive on the test very early,
while others with low hCG may not show up until after
the first missed period. In a recent study, reported in
the Journal of American Medical Association, 10% of 250
women tested had not even implanted by the first missed
period. Therefore, their hCG was so low that no urine
test could detect it.
How early can LifeChoices' Pregnancy Tests give
positive results?
Because our test is so sensitive, it may pick up a
positive result as early as 7 - 10 days post conception
(21 to 24 days after the first day of the last period)
depending on when implantation occurs and the client's
personal hCG levels. If hCG is detected at this early
stage, the test line would be expected to be light as
hCG levels are just beginning to build. However, when
testing this early, the results should be verified after
the first missed period. This is because, although the
test picks up the presence of hCG, it does not guarantee
a viable pregnancy. hCG may also be produced by an EPL
or "early pregnancy loss". This is an embryo which fails
to implant properly in the uterus, or is rejected by the
uterus. It is followed by a normal or slightly heavier
than normal menstrual period, which may be 2 to 3 days
late. hCG levels may rise in the week following
implantation (second week of conception) like a
normal-term pregnancy. When EPL occurs, hCG
concentration in the urine reaches a peak 2 weeks after
conception then rapidly declines.
What is the significance of Early Pregnancy Loss
(EPL)?
Most women are unaware that they have had an EPL. EPL's
are much more common than people realize. Some reports
indicate that EPL's may occur in 31% of pregnancies
overall. CPC lay counselors need to be aware that women
may get a positive result from a test taken before the
first missed period. However, the fertilized egg may not
implant correctly, or the uterus may reject the embryo.
An EPL can delay menses up to three days which would
further lead the client to believe she is pregnant,
while in reality that is no longer the case.
Can this explain why two tests, taken a few days
apart, give conflicting results?
Yes it can. This happened to a woman at one center. A
young man took home a pregnancy test a few days before
she missed her period and it was positive. She then came
to the center a week later and was sure she was pregnant
her period still had not started. But the center's test
come back negative. By the time she came to the center
she had experienced an Early Pregnancy Loss. Her hCG had
dropped to undetectable levels. The woman was urged to
get a blood test, which verified the center's results.
It is good to understand this issue as you may have a
similar case occur.
If you tested before your first missed period should
you be retested if your period still has not started after
31 days?
Yes. If you test earlier than 31 days, you should know
that even if it is negative, a test should be given at
31 days to verify the results if your menses has not
started. This is because your hCG level may have been
too low to register on the first test. Or, if it reads
positive, you should be advised that there is still a
chance of Early Pregnancy Loss. It is our
recommendation, and that of the leading hCG researcher,
Dr. Laurence Cole of the University of New Mexico, that
any test that indicates possible pregnancy before 31
days after the start of the last menses should be
repeated on or after the 31st day. This assures accurate
detection of a viable pregnancy.
Are there any other factors that may give
conflicting test results at two different times?
Yes. Another factor is how diluted the urine is at the
time of the test. The more concentrated the urine, the
greater the concentration of the hCG. Remember, woman's
levels of hCG can vary markedly. If a woman who has low
levels of hCG takes a pregnancy test early in her
pregnancy using her first morning urine, it may come out
positive because of higher concentrations of hCG. If she
then goes to a center later in the day after consuming
liquids, her urine will be very diluted and there may
not be a high enough level of hCG to detect. If there is
a question about the test results, confirm results by
retesting using a first morning sample.
For early pregnancy tests, should you give us your
first morning urine?
Yes. In fact, when results vary or are questionable, you
should be retested with the first morning urine. If this
is not possible, you need to limit liquid intake and go
as long as possible without urinating before you come
in. Remember, the more concentrated the urine is, the
more concentrated the hCG will be. In such cases it may
also be a good idea to wait 48 hours before retesting so
that the hCG level can double to a more detectable
level.
Are there any other conditions that may produce
false readings?
There are some medical conditions that will skew the
test results. They are complicated and uncommon. If you
test negative after 31 days and your period does not
start, you should be encouraged to see your doctor. He
will be able to order a blood test that will determine
if hCG is present and if there are any medical concerns.
If you test positive as the result of a medical
condition, the doctor will be able to advise you on
further medical care.
How does the information that you provide play a
role in the testing?
When conducting pregnancy testing it is important to
remember that a center is relying on your self reporting
about the last menses, the regularity or irregularity of
your menstrual cycles, and your sexual activity.
How are LifeChoices' Pregnancy Tests done?
To use the test, place it on a level, dry surface and
put on protective gloves. Then take the dropper from the
package and squeeze the bulb at the top of the dropper
to remove the air. Place the tip of the dropper in the
urine and release the bulb while holding the dropper
upright. While continuing to hold the dropper upright,
squeeze the bulb to release four drops of urine in close
succession into the sample well. After the urine has
moved across the testing window, set your timer for five
minutes and wait for the results. Do not immediately
dispose of the urine in case there is any need to redo
the test. Within four minutes the control line "C" will
begin to turn pink. If the test is positive, another
pink line will appear under the "T" or Test zone. If the
test is negative, the zone under the "T" will not change
color. The test line may show a variety of shades of
pink from light to bright depending on the levels of hCG.
If any shade of pink appears, even a very slight line,
the test should be considered positive. If no pink line
occurs in the control zone "C" the test is invalid. High
sensitivity urine-based pregnancy tests performed on
specimens containing levels of hCG below 20 mIU may show
color development over time, indicating the need to
restest in 48 hours. Do not read the test after 10
minutes.
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24-Hour Option Line
800-638-1023
417-624-8030
Contact Information
Office: 417-623-0131
Fax: 417-624-8341
Address:
531 E 7th St
Joplin, MO 64801
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